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A history of severe reflux, bariatric surgery, opioid use, Parkinson disease, scleroderma, gastric outlet obstruction, or long-standing diabetes should raise suspicion for baseline motility impairment

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This reduction can leave us more susceptible to oxidative stress and related health issues

Awarded the Nobel Prize for Chemistry in 1958, Sangers method opened up a new pathway to the structural identification of gut hormones

A gradual dose increase often helps ease these effects